Langerhans cell histiocytosis hematology and oncology. Lch, eosinofilt granulom, hand schullerchristians sjukdom, histiocytosis x, letterersiwes sjukdom icd10. Click on the image or right click to open the source website in a new browser window. Langerhans cell histiocytosis eosinophilic granuloma of bone in. Hand schuller christian disease hsc primarily affects infants and children. Langerhans cell histiocytosis lch and erdheimchester disease ecd share similar clinical features and mechanisms. Handschullerchristian disease with condylar aplasia.
Handschullerchristian disease is associated with multifocal langerhans cell histiocytosis. Tosssurvey of handschuller christiandisease in otolaryngology. The full text of this article is available in pdf format. Condylar aplasia, handschullerchristian disease, langerhans cell histiocytosis, oligodontia. Histiocytosis, handschullerchristian disease, langerhan cell. Here we report such a patient, who was first diagnosed with hand schuller christian disease hsc, a type of lch. Handschullerchristian disease bhargava d, bhargava k, hazarey. To describe the clinical case of a monthold boy with handschullerchristian disease. Haslam department of neurology, the university of kentucky medical center, 800 rose street, lexington, kentucky 40506, u.
Lch is clinically classified into three typeseosinophilic granuloma, hand schuller christian disease and abtletterer siwe disease. During recent years the relationship between handschullerchris. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. It is associated with a triad of exophthalmos, lytic bone lesions. In very rare circumstances, the two diseases coexist in the same patient. A saviour in a child with hand schuller christian disease for mri. This article has presented the classification of hand schuller christian disease and discussed the use of a new antineoplastic drug velban in its treatment. The three classic symptoms are softened areas of the skull and other. Handschullerchristian hsc disease is a rare proliferative disorder in which pathological langerhans cells lcs. Previously referred to as handschullerchristian syndrome, it is characterized by the classical triad of lytic bone lesions. Langerhans cell histiocytosis lch is a dendritic cell antigenpresenting cell disorder. Handschullerchristian hsc disease is a rare proliferative disorder in which pathological. The relationship of handschullerchristians disease, letterer. Also, the case of a 4yearold boy with an extremely advanced mandibular lesion has been described.
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